KPV UK — Alpha-MSH Tripeptide Research Guide
Also known as Lysine-Proline-Valine
KPV is the three-residue C-terminal fragment of alpha-MSH — lysine, proline and valine. Despite being one of the smallest peptides in the catalogue, it has a well-defined research profile.
This page covers why a tripeptide fragment is studied separately from its parent hormone, and how KPV differs from the repair peptides it is often listed alongside.
For in vitro research use only — not for human or animal consumption. Not a licensed medicine in the UK. Nothing on this page is medical advice.
What is KPV?
Alpha-MSH has documented anti-inflammatory activity in research models alongside its pigmentation-related signalling. KPV isolates the C-terminal tripeptide, which retains much of the anti-inflammatory research profile without the melanocortin receptor activity of the full sequence.
That separation is the point of the fragment: it allows one property of the parent hormone to be studied without the others.
Research context
Published preclinical work examines KPV in models of intestinal and mucosal inflammation, and in cytokine-signalling assays including NF-κB pathway activity. Its very small size is thought to contribute to good tissue distribution in those models.
This literature is preclinical. KPV is not a licensed medicine and is supplied for in vitro research use only.
How KPV differs from BPC-157 and TB-500
BPC-157 and TB-500 are studied primarily in tissue-repair and angiogenesis models. KPV is studied in inflammation and cytokine signalling. They are frequently listed together under recovery research but address different mechanisms.
Handling and storage
Supplied lyophilised in a 10mg vial. Reconstitute with bacteriostatic water added slowly down the vial wall, swirl gently until clear, refrigerate at 2–8°C and use within 28 days.
Buying this peptide in the UK
- UK-held stock — same working day dispatch on orders before 2pm, Mon–Fri.
- Royal Mail Tracked 24 with photo confirmation on every parcel.
- Independent HPLC and mass-spec testing with a batch-matched Certificate of Analysis.
- Discreet plain packaging and normal UK card checkout — no crypto required.
- Free 4 needles + 4 alcohol swabs with every vial — opt in at checkout.
Related guides
Browse related products
View full shopFrequently asked questions
Is KPV related to Melanotan?
Both derive from alpha-MSH, but KPV is only the three-residue C-terminal fragment and does not carry the melanocortin receptor activity that the Melanotan analogues are studied for.
Is KPV legal in the UK?
KPV is legal to buy and possess in the UK for laboratory research purposes. It is not a licensed medicine in the UK, is not prescribed by the NHS, and is supplied strictly for in vitro research use only — not for human or animal consumption.
How is KPV reconstituted?
KPV is supplied lyophilised. Add bacteriostatic water slowly down the inside wall of the vial and swirl gently — never shake, as agitation can damage the peptide chain. Once dissolved, store at 2–8°C and use within 28 days. Use our free peptide calculator for exact volumes rather than following generic charts.
Do you supply a Certificate of Analysis for KPV?
Yes. Every batch is independently HPLC and mass-spec tested and the batch number on the vial matches a published Certificate of Analysis, so purity can be verified before use.
How fast is UK delivery?
Stock is held in the UK. Orders placed before 2pm Monday–Friday are dispatched the same working day by Royal Mail Tracked 24 with photo confirmation, in discreet plain packaging with no product names on the outside.
Disclaimer: All products sold by Peptides UK 4U are for laboratory and research purposes only. They are not intended for human or animal consumption, diagnosis, treatment or prevention of any disease.