What is Tesamorelin?
Tesamorelin is a stabilised analogue of growth hormone-releasing hormone. Native GHRH is degraded within minutes by dipeptidyl peptidase-4; Tesamorelin attaches a trans-3-hexenoyl group to the N-terminus, which slows that breakdown dramatically while keeping the receptor-binding portion of the molecule intact.
- Class: synthetic GHRH analogue
- Scientific name: Tesamorelin acetate
- Structure: GHRH(1-44) with an N-terminal hexenoyl modification
- Supply: 10mg lyophilised vial, ≥98% purity
The research context
In laboratory settings Tesamorelin is studied for its interaction with the GHRH receptor and the downstream endocrine signalling pathways associated with it. Research applications focus on receptor binding activity, peptide stability under different storage conditions, and hormone-pathway modelling.
It has one of the larger datasets in the GHRH family because it has been through formal clinical study overseas. None of that constitutes evidence of a human outcome for material supplied here, and our Tesamorelin is not for human use.
Tesamorelin vs Ipamorelin vs CJC-1295
| Peptide | Receptor | Notes |
|---|---|---|
| Tesamorelin | GHRH receptor | Full-length GHRH(1-44) analogue, largest dataset. |
| CJC-1295 | GHRH receptor | Modified GHRH(1-29) fragment; with or without DAC. |
| Ipamorelin | Ghrelin receptor (GHS-R) | Secretagogue — different point in the same axis. |
See also the CJC-1295 + Ipamorelin blend guide.
How to reconstitute Tesamorelin
Tesamorelin is one of the peptides that needs acetic acid water first — bacteriostatic water alone will not fully dissolve it.
- Wipe the stopper with an alcohol swab and allow it to dry.
- Add 0.5ml of acetic acid water and swirl until fully dissolved.
- Then add 2.5ml of bacteriostatic water.
- Swirl gently — never shake.
- Label with concentration and date, refrigerate at 2–8°C.
For any other target concentration, use the free peptide reconstitution calculator.
Purity, testing & UK delivery
- Independently HPLC and mass-spec tested, ≥98% purity.
- Batch Certificates of Analysis published openly.
- UK-held stock — same working day dispatch before 2pm, Mon–Fri.
- Royal Mail Tracked 24 with photo confirmation, discreet plain packaging.
- Free 4 needles + 4 alcohol swabs with every vial — opt in at checkout.
Related guides
Frequently asked questions
What is Tesamorelin?
Tesamorelin is a synthetic analogue of growth hormone-releasing hormone (GHRH). It is a 44-amino-acid peptide with a trans-3-hexenoyl group attached to the N-terminus, a modification that makes it far more resistant to enzymatic breakdown than native GHRH.
Where can I buy Tesamorelin in the UK?
Peptides UK 4U holds Tesamorelin 10mg in UK stock at £59.99, dispatched the same working day on orders placed before 2pm Monday to Friday by Royal Mail Tracked 24.
How much is Tesamorelin in the UK?
A Tesamorelin 10mg vial is £59.99 including UK stock and same-day dispatch. Free 4 needles and 4 alcohol swabs are included with every vial when you opt in at checkout.
What is the difference between Tesamorelin and Ipamorelin?
They act on different receptors. Tesamorelin is a GHRH analogue and binds the GHRH receptor. Ipamorelin is a growth hormone secretagogue that acts on the ghrelin receptor (GHS-R). They are studied at different points in the same signalling axis, which is why they appear together in research protocols rather than as substitutes for each other.
What is the difference between Tesamorelin and CJC-1295?
Both are GHRH-based. CJC-1295 is a modified GHRH(1-29) fragment; Tesamorelin is a full-length GHRH(1-44) analogue with a hexenoyl modification. Tesamorelin has the larger clinical research dataset behind it, having been studied as a licensed compound overseas.
How is Tesamorelin reconstituted?
Tesamorelin is supplied lyophilised. Add 0.5ml of acetic acid water first and swirl until fully dissolved, then add 2.5ml of bacteriostatic water. Never shake — swirl gently. Use the free peptide calculator to confirm your target concentration.
How should Tesamorelin be stored?
Store unopened lyophilised vials cool and dry, or at -20°C for extended stability. Once reconstituted, refrigerate at 2–8°C, protect from light and avoid repeated freeze-thaw cycles.
What purity is your Tesamorelin?
Every batch is tested to at least 98% purity by RP-HPLC with mass-spec confirmation, and the batch number on the vial matches a published Certificate of Analysis.
Is Tesamorelin legal in the UK?
Tesamorelin is legal to buy and possess in the UK for laboratory research purposes. It is not a licensed medicine in the UK, is not prescribed on the NHS, and is supplied strictly for in vitro research use only — not for human or animal consumption.
Do you supply a Tesamorelin pen?
Tesamorelin is supplied as a lyophilised vial. Our pre-filled Quick Pen preparation is available as a checkout add-on on suitable products — see the peptide pens page for the current list.
Disclaimer: All products sold by Peptides UK 4U are for laboratory and research purposes only. They are not intended for human or animal consumption, diagnosis, treatment or prevention of any disease.