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SS-31

SS-31 UK — Elamipretide, Cardiolipin & Mitochondrial Research

Also known as Elamipretide

SS-31, also known as Elamipretide, is a cell-permeable tetrapeptide that concentrates at the inner mitochondrial membrane. It belongs to the Szeto-Schiller peptide series, which is where the SS designation comes from.

It is one of the few research peptides with a clearly defined subcellular target: the phospholipid cardiolipin.

For in vitro research use only — not for human or animal consumption. Not a licensed medicine in the UK. Nothing on this page is medical advice.

What is SS-31?

SS-31 is a four-amino-acid peptide with an alternating aromatic-cationic structure. That structure allows it to cross cell membranes without a transporter and to accumulate selectively at the inner mitochondrial membrane, in concentrations far above the surrounding cytosol.

Cardiolipin and the mechanism

Cardiolipin is a phospholipid found almost exclusively in the inner mitochondrial membrane, where it organises the components of the electron transport chain. Published research describes SS-31 as binding cardiolipin and being studied for its effect on cristae structure and electron transport efficiency.

This is preclinical and clinical research literature, summarised for context. SS-31 is not a licensed medicine in the UK and is supplied for in vitro research only.

SS-31 vs MOTS-c

SS-31 is a structural/membrane-targeted peptide — it goes to a specific place and binds a specific lipid. MOTS-c is a signalling peptide associated with the AMPK pathway. Research programmes that involve both treat them as complementary rather than interchangeable.

Handling and storage

Supplied lyophilised in 50mg vials. Reconstitute with bacteriostatic water added slowly down the vial wall, swirl gently, refrigerate at 2–8°C and use within 28 days. Avoid light exposure and repeated freeze-thaw cycles.

Buying this peptide in the UK

  • UK-held stock — same working day dispatch on orders before 2pm, Mon–Fri.
  • Royal Mail Tracked 24 with photo confirmation on every parcel.
  • Independent HPLC and mass-spec testing with a batch-matched Certificate of Analysis.
  • Discreet plain packaging and normal UK card checkout — no crypto required.
  • Free 4 needles + 4 alcohol swabs with every vial — opt in at checkout.

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Frequently asked questions

Is SS-31 the same as Elamipretide?

Yes. SS-31 is the research designation from the Szeto-Schiller peptide series; Elamipretide is the name used in the clinical development literature for the same molecule.

Is SS-31 legal in the UK?

SS-31 is legal to buy and possess in the UK for laboratory research purposes. It is not a licensed medicine in the UK, is not prescribed by the NHS, and is supplied strictly for in vitro research use only — not for human or animal consumption.

How is SS-31 reconstituted?

SS-31 is supplied lyophilised. Add bacteriostatic water slowly down the inside wall of the vial and swirl gently — never shake, as agitation can damage the peptide chain. Once dissolved, store at 2–8°C and use within 28 days. Use our free peptide calculator for exact volumes rather than following generic charts.

Do you supply a Certificate of Analysis for SS-31?

Yes. Every batch is independently HPLC and mass-spec tested and the batch number on the vial matches a published Certificate of Analysis, so purity can be verified before use.

How fast is UK delivery?

Stock is held in the UK. Orders placed before 2pm Monday–Friday are dispatched the same working day by Royal Mail Tracked 24 with photo confirmation, in discreet plain packaging with no product names on the outside.

Disclaimer: All products sold by Peptides UK 4U are for laboratory and research purposes only. They are not intended for human or animal consumption, diagnosis, treatment or prevention of any disease.

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