PT-141 UK — Bremelanotide, Melanocortin Receptors & Research Use

PT-141 is a cyclic heptapeptide that arose as an active metabolite of Melanotan 2. Where MT-2 has significant activity at MC1R — the receptor associated with pigmentation — PT-141 shifts the balance toward MC3R and MC4R, the central melanocortin receptors.

There are five melanocortin receptors. MC1R is associated with pigmentation, MC2R with adrenal signalling, and MC3R/MC4R with central nervous system pathways including appetite and arousal signalling in published research. PT-141's research profile is centred on the latter group.

MT-2 is broadly active across the melanocortin receptors including strong MC1R engagement, which is why pigmentation dominates its research literature. PT-141 has comparatively reduced MC1R activity and is studied for the central receptors instead.

PT-141 is available as a lyophilised 10mg vial and as a pre-filled nasal spray format. Sealed vials should be stored refrigerated at 2–8°C and away from light.

• UK-held stock — Same-day Royal Mail Tracked 24 dispatch on orders by 1pm, Monday to Friday.
• Royal Mail tracked with photo confirmation on every parcel.
• Independent HPLC and mass-spec testing with a batch-matched Certificate of Analysis.
• Discreet plain packaging and normal UK card checkout — no crypto required.
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