MOTS-c 40mg
Metabolic
Overview
MOTS-c 40mg is a synthetic mitochondrial-derived peptide supplied as a lyophilised powder for laboratory research use. It is selected within controlled environments for investigation into peptide structure, mitochondrial signalling, and cellular pathways.
Classification: MOTS-c — a 16 amino-acid mitochondrial-derived peptide encoded within the 12S rRNA region of the mitochondrial genome.
Research background
Within laboratory settings, MOTS-c is studied for its interaction with mitochondrial processes and associated cellular pathways. Research applications focus on peptide stability, intracellular activity, and pathway modelling under controlled experimental conditions.
This summary describes published preclinical and, where applicable, clinical research. It is not a medical claim and does not describe or endorse any human use of the compound as sold by Peptides UK 4U.
Mechanism of action (under investigation)
Published research investigates MOTS-c as a regulator of AMPK signalling, mitochondrial folate/methionine metabolism and cellular metabolic homeostasis. In vitro and rodent studies examine its role in glucose uptake and mitochondrial biogenesis.
Laboratory handling
This product is typically reconstituted using bacteriostatic water or a suitable sterile solvent within a controlled laboratory setting. All handling should be carried out by qualified professionals using appropriate sterile techniques and safety procedures.
Storage & stability
- Store in a cool, dry environment before reconstitution.
- For extended stability, storage at -20°C is recommended.
- Avoid repeated freeze-thaw cycles after reconstitution.
For reconstitution volumes and target working concentrations use our peptide calculator. We do not publish dosing protocols for human use.
Product specifications
- Peptide Type
- Mitochondrial-derived peptide
- Form
- Lyophilised powder
- Quantity
- 40mg
- Purity
- ≥98% (subject to batch testing)
- Appearance
- White lyophilised powder
- Solubility
- Water soluble
- Stability
- Maintains integrity under controlled storage conditions
- Manufacturing Standard
- Produced in controlled laboratory environments
Certificate of Analysis: Available on request from our support team.
Frequently asked questions
What is MOTS-c studied for in research?
MOTS-c is a mitochondrial-derived peptide investigated in vitro for its role in cellular metabolism, insulin-sensitivity signalling and mitochondrial-nuclear communication under controlled laboratory conditions.
What purity is your MOTS-c?
Every 40mg vial is tested to ≥98% purity by RP-HPLC. A batch-specific Certificate of Analysis is available on request.
How is MOTS-c reconstituted?
Reconstitute the lyophilised powder with bacteriostatic water in a sterile laboratory environment — see our peptide calculator for target concentrations. Prepare working aliquots to minimise freeze-thaw cycles.
How is MOTS-c different from NAD+ in research use?
MOTS-c is a peptide that signals through metabolic pathways such as AMPK; NAD+ is a coenzyme central to redox and sirtuin activity. They are frequently compared in mitochondrial-function research.
References
- Lee C et al., Cell Metabolism 21(3):443–454 (2015) — discovery of MOTS-c
- Kim SJ et al., Cell Reports 22(2):342–354 (2018) — MOTS-c and metabolic homeostasis
References are provided for educational context. Citation does not imply endorsement of any specific use.
Disclaimer: This article is provided for laboratory and educational purposes only. It is not medical advice and does not describe or endorse any human use. All products sold by Peptides UK 4U are for laboratory research only, are not for human or veterinary consumption, and are not intended to diagnose, treat, cure or prevent any disease.